First Five is our list of essential media for the month which spans a range of content including scientific papers, books, podcasts, and video. For our full list of interesting media in health and science, updated regularly, follow us on Twitter or Instagram.
1/ Our Animal Friends
A group in Sweden has published a new dog reference genome that has 55-fold better coverage than the prior reference genome. The paper notes that “domestic dogs have lived alongside humans for at least 10,000 years, and during this time, they have adapted to a shared environment and diet, while being selectively bred for traits such as morphology and behaviour. Humans and dogs also share orthologous genes, genomic architecture and disease sets, placing the dog as an important comparative species for human genetics and genomics. Taking advantage of pet dog medical records, within breed homogeneity and disease risk enrichment, it has been possible to provide insights into both rare and common spontaneous disease.” So our best animal friends are not just our companions, but helping us to understand who we are and how we can stay healthy.
Access to a closer animal neighbor to humans is proving to be an issue for developing vaccines to protect us from future pandemics. Once again illustrating the importance of our relationship to other members of the animal kingdom.
2/ Fantastic Voyage
Those of us of a certain age will recall a film called Fantastic Voyage that was premised on a technology that allowed people to be shrunk to microscopic size and then sent into the body of an injured scientist to repair his damaged brain. Turns out that science fact is catching up to science fiction at a company called Bionaut Labs.
3/ More Science Fiction / Science Fact
Another familiar trope in the science fiction/fantasy realm are zombies. Recently published research finds that gene expression in some brains cells actually increases after death. Which is both weird and a bit zombie-like. Of practical significance is making sure to take into account these post-mortem changes to ensure that researchers are interpreting findings on human brain tissues accurately which could impact our understanding of disorders such as autism, schizophrenia and Alzheimer's disease.
4/ Gut Science
Lots of interesting things going on in our guts these days:
– A Cell paper from researchers at NIH reports that the body's natural defenses against bacterial infection are helped by a nutrient—taurine—that causes the gut to recall prior infections and kill invading bacteria.
-–A study in Science Advances shows how gut bacteria could be directly and indirectly affecting brain disease such as Parkinson’s.
– Another Cell paper reports that common gut fungi teach the immune system how to respond to their more dangerous relatives. Things don’t go so well if this process fails for any reason.
– And finally, one more paper from Cell, proteomics analysis indicated that intermittent fasting may not be a good way to lose belly far, but it still may be good for you.
5/ How Old Are You Really?
All though we all count our age the same way using chronological age, our biological ages do not necessarily perfectly correlate with this method. Researchers in Germany have developed a a transcriptome-based aging clock that predicts biological age with an accuracy that is close to the theoretical limit.
This age clock could find wide application in genetic, nutritional, environmental, and therapeutic interventions in the aging process. And is just another example of the amazing research happening widely around the world.
We’re excited to announce the promotion of both Amit Bansal and Sam Bjork to Partner at Digitalis Ventures.
Amit Bansal was a part of the founding team at Digitalis. Since our inception in 2016, Amit has led or co-led our firm’s investments in Aunt Bertha, The Mighty, Brella Insurance, Cayaba Care, Unifi Health, NuPerfect, and Smalls. Beyond his investing activities, he has played an important role in all aspects of our internal operations.
Amit is also a member of the NYU Innovation Fund’s Healthcare Advisory Board and on the Board for the Fund for Public Health NYC. Prior to Digitalis, Amit was at Mars, Inc. in both strategy and innovation roles. He has also helped to scale a healthcare start-up leveraging telemedicine to provide last mile access to primary care in rural India. Amit began his career at GE Healthcare in corporate finance, where he held roles in finance, risk, and marketing. He received his MBA from Northwestern University’s Kellogg School of Management and his BA from Boston College.
Since joining Digitalis in 2017, Sam Bjork has led or co-led our firm’s investments in Good Therapeutics, Terray Therapeutics, Onc.AI, PetMedix, Scout Bio, Rejuvenate Bio, Code Ocean, Elemental Machines, and an unannounced genomics company. He has sourced, led, or co-led our investments in five other companies across our three practice areas, including NuPerfect and Cayaba Care, and he has played a critical role in establishing our company creation capabilities.
He received graduate degrees from Cambridge and Oxford University as a Marshall Scholar and an A.B. in Chemistry from Harvard University. Prior to Digitalis, Sam was a member of the healthcare and clean energy practices at the Boston Consulting Group.
Congratulations to both Sam and Amit for this well deserved recognition.
Participated in Series Seed investment with Flare Capital and Kapor Capital.
Cayaba Care provides holistic and personalized at-home maternity services for Medicaid populations, including urgent care, prenatal care, postpartum care, and mental health services. Learn more here.
Aunt Bertha named the top performer in 2021 Best in KLAS report in Social Determinants of Health Networks category
PR Newswire >
A Third of Americans Plan to Raid Their Retirement Savings to Make Ends Meet
Idaho HIE reduces duplication rate to less than 1% with MPI tech
Healthcare IT News >
Essentia Health connects people with free and reduced-cost services
Brainerd Dispatch > Duluth News Tribune >
Better Benefits Podcast Episode #11: Health Benefits 2021 Outlook with Amit Bansal
AccuRisk Solutions Partners with Brella Insurance to Bring Innovative Supplemental Health Insurance to Texas Employers
Public Opinion >
Sidecar Brings Modern Indemnity Health Insurance to Utah
Strength Seen in Champions Oncology, Inc.
Yahoo Finance >
DeepMatter inks co-distribution deal with Elemental Machines
Morningstar > MarketScreener >
Q&A: Why the Lab Manager Title May Be Going Away
Laboratory Equipment >
What’s Next for Smart PPE
EHS Today >
Small Business, Big Mission: Startup Kenzen embodies KC area's opportunities
Kansas City Business Journal >
Kenzen Launches Data Dashboard That Analyzes Safety and Productivity of Workers in Hot and Humid Conditions
Med Tech Outlook >
Portfolio Job Opportunities
Digitalis Portfolio Companies Are Hiring
See Open Positions >
Public-Interest Technologies for Better Health
Digitalis Commons is a non-profit that partners with groups and individuals striving to address complex health problems by building public-interest technology solutions that are frontier-advancing, open-access, and scalable.
Digitalis Commons continues to support Columbia University’s Program for Diversity and Inclusion in Commercialization and Entrepreneurship (DICE). The program offers among other efforts the possibility to meet with experienced life science entrepreneurs, industry executives, and venture capitalists through fireside chats, breakfasts, and lunch breaks. As part of this effort Digitalis’ Jonathan Friedlander is holding office hours every Monday during the length of the program to share his experience in VC and entrepreneurship and help participants navigate through the transition from the laboratory to the industry.
February 2021 Edition / Climate and Health >
January 2021 Edition / Health Equity >
December 2020 Edition / 2020 and Lung Inflammation >
November 2020 edition / Thoughts for Food >
October 2020 Edition / Show Unfinished Work >
September 2020 Edition / Can we learn how to control fat metabolism? >